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Ferroptosis and ischemic/reperfusion related diseases I/R injury is a complex physiological event that occurs when blood supply to a tissue or organ is disrupted and then subsequently restored [321, 322]
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(2011) Alterations of red blood cell metabolome in overhydrated hereditary stomatocytosis
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Among glutamic acid, cysteine, and glycine, cysteine is found at a lower concentration in plasma and tissues, and cysteine is thus the rate-limiting substrate in GSH biosynthesis
