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Initially, studying desensitization was made possible by using experimental models endogenously expressing OR such as brain membranes, rabbit cerebellum or cell lines (NG 108-15, SH-SY5Y, SK-N-SH, SK-N-BE)

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An 8-week randomized double-blind trial compared GHK-Cu in a nano-lipid carrier against Matrixyl 3000 and found a 55.8% reduction in wrinkle volume versus control serum, along with a 32.8% reduction in wrinkle depth

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10.3390/ijms20246196 [DOI] [PMC free article] [PubMed] [Google Scholar] 5.Bi W, He C, Ma Y, Shen J, Zhang LH, Peng Y, et al