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In a rat model of neuropathic pain induced via sciatic nerve ligation, treatment with bromelain resulted in significant reductions in thermal hyperalgesia and mechanical allodynia [154]

Probiotic and intra-nasal oxytocin combination therapy on autonomic function and gut-brain axis signaling in young children and teens with autism spectrum disorder
The product described here has not been conclusively evaluated by the Food and Drug Administration (FDA

10.1038/s41398-018-0353-x [DOI] [PMC free article] [PubMed] [Google Scholar] 72.Cao B, Jin M, Brietzke E, Mcintyre R, Wang D, Rosenblat J, et al