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Furthermore, in humans and human cells, L-NAC has shown efficacy in (1) treating methamphetamine dependence 23 and craving in SUD (Supplemental Table 1) 24,25 , (2) modulating the cysteine redox proteome in neuro-degenerative diseases 26 and overcoming the down-regulation of anti-oxidant genes 27 , (3) acting as a pre-emptive drug to ameliorate post-operative pain 28 , (4) providing a new prominent approach for treating psychiatric disorders 29 , and (5) preventing/ameliorating peripheral neuropathies 30

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Advanced glycation end-products and arterial stiffness in hypertension