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Contrarily, BPC 157 therapy counteracted the damaging effect of systemic administration of high doses of capsaicin (milligrams per kilogram range, long-lasting damage of somatosensory neurons, more when given in newborn animals)

L-Glu also triggered the downregulation of antiapoptotic B-cell lymphoma-2 (Bcl-2) expression [51,58,59,62], upregulation of the Bax/Bcl-2 ratio [64], and release of other proapoptotic proteins, such as cytochrome c [58,61]

Moreover, reduced expression of profibrotic proteins and CTGF were also observed in those mice (Chiao et al., 2012)

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