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Description
The agency cited immunogenicity risks (peptides can trigger anti-drug antibodies with repeated injection), manufacturing impurity concerns (endotoxin contamination, truncated sequences, diastereomers), and the absence of robust human clinical data for most compounds
Because Vitamin B12 is mainly found in animal-based foods, supplementation may be especially relevant for people following plant-based or low-animal-product diets
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IP administration creates rapid systemic spikes and clearance, triggering acute stress-response pathways
Read our CJC-1295/Ipamorelin research guide for more context
