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GSK-3 inhibitor administration alone provided superior plaque reduction effect both in cortex and hippocampus than FUS exposure and can reach statistical difference (31.6% reduction to 0.39 0.02%, p = 0.0446 in cortex

Su X, Shen Z, Yang Q, et al

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In addition to supporting biosynthesis, NADPH produced in the oxPPP can be either antioxidant or pro-oxidant
doi: 10.1248/bpb.31.602
