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Given their separate mechanisms, any potential interactions are purely speculative and would require rigorous scientific investigation

If youre considering B12 therapy, Trim Body M.D

J Agric Food Chem 43:21872194

Down Regulation: the number of receptors decreases (by proteolysis) upon exposure to a high concentration of agonist for a very long time (hours), making the cell less responsive to the same agonist or others that work at the same receptor

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