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doi: 10.1017/S002966511000159X 19 De LeBlancA

Before we dive deeper, consider this: 2

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It has been reported that HT patients exhibit abnormal DNA methylation patterns, which are important epigenetic changes that contribute to gene silencing and lead to changes in gene expression (Pu And Zhang 2024)

For additional background, you can review this PubMed overview on GHK and tissue remodeling