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149 An alternative means of linking a bile acid to a platinum(II) center involves conjugation to the nonleaving group ligands, a strategy that has afforded complexes demonstrating activity in cultured cells via a mechanism of action similar to that of cisplatin

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Deficiency in B6 results in impairment of the cystathionine -synthase and cystathionine lyase catalyzed reactions, both of which require B6 (pyridoxal phosphate, PLP) as cofactor