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To date, these stages have remained theoretical, lacking specific numerical indicators to define transition points
Research consistently shows that 80-90% of sciatica cases resolve with conservative, non-surgical treatment
Historically these cells are not linked to demyelination following cuprizone treatment because the loss of the V(D)J recombination activation gene-1 (RAG-1), which is critical for B- and T- lymphocyte generation [269], does not alter demyelination and T-cell accumulation in the corpus callosum [46, 270]
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