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Post-Exertional Malaise (PEM): While not a cure for PEM, improving mitochondrial efficiency and reducing systemic oxidative stress can help raise a patient's energy envelope, making them slightly more resilient to the metabolic fallout of physical or cognitive exertion
It is especially beneficial for those who have challenges with obtaining and absorbing adequate B12 from the diet
MOTS-c is a mitochondrial-derived peptide that influences how cells use glucose and fat for energy, described as mimicking some of the metabolic effects of exercise at a cellular level, with reported benefits including increased stamina and reduced belly fat
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