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(1984) Importance of raised growth hormone levels in mediating the metabolic derangements of diabetes

Indeed, as noted in the guidelines and consensus statements 9,25,26 , the presence of dysfunction of the GH-IGF-1 axis is suspected when high ( + 2.0) or low ( 2.0) IGF-1 SDS is detected in clinical practice

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However, these reports are largely anecdotal and not substantiated by controlled clinical studies

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