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For vaccine induced protection against mycobacterial infections, CD4+ cells are vital and multiple studies have demonstrate that CD8+ cells play critical role in controlling mycobacterial infections via perforin, granzymes, and granulysin ( ex-vivo result of the IcL group is more difficult to interpret as the primed PBMCs indicated higher survival rate for MAP compared to macrophage alone or incubated with unprimed PBMCs

Dietitians can assess micronutrient intake and recommend targeted supplementation when indicated

Compliance matters for outcomes, and simpler protocols generally produce better adherence

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