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Increased ventricles and sulcal dilatation are a consequence of neuron degeneration within the brain

The proposed chain of effects looks like this: NNMT inhibited nicotinamide is no longer inactivated by methylation and becomes available for conversion to NAD+

J Neurochem 39: 14921495, 1982

Users of Glutathione Nasal Spray sometimes report brighter skin and a cleaner look after consistent use
