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Its targeted mechanism makes it a valuable tool for researchers studying enzyme-driven metabolic regulation, pathway efficiency, and integrated cellular energy systems.

We conclude by describing the relevant targets of crosstalk of these PCDs, pointing out that some of the drugs targeting the targets are effective in mitigating DPN progression and neuroinflammation, but there is still a therapeutic void for important targets like p53

Selective permeability: Small lipophilic molecules pass relatively freely

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10.1038/nature14344 Summary Keywords iron deficiency, tumor progression, immune response, tumor metabolism, therapeutic targets Citation Lin L, Yin X and Guan Y (2025) Decoding iron deficiency in cancer: mechanisms, immune modulation, and therapeutic potential