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doi: 10.1002/mds.26069 54

On the other side of the spectrum, the only FDA-approved glutamine therapy is in sickle cell disease (SCD) patients of all ages based on a Phase III clinical trial where L-glutamine was well tolerated and reduced pain crisis [96]

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Incorporating combinations of compounds as therapeutic agents offers various benefits over employing a single molecule in higher concentrations [198]

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