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The amounts of total reduced and oxidized glutathione were quantified using a modified Tietze method by Adams ( Safety Measurements Any adverse event during the course of the study was monitored and reported to the study staff at week 6 (visit 5) or week 12 (visit 8) in the clinic or directly to the principal investigator throughout the study

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Lastly, the released l-Glu also is capable of mediating an autocrine/paracrine signal that enhances invasive and migratory properties through the activation of Ca 2+ permeable AMPA receptors on the glioma cells themselves (Lyons et al ., 2007

doi:10.1038/s41598-021-96578-z (3) Sandra Dez-Villares, et al

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