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Additionally, reduced intracellular Cu causes a deficiency or functional impairment of lysyl oxidase (LOX) and significantly reduces CCO activity (114)

Mildcomparable to other subcutaneous peptides

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33 ) but also an altered GSH conjugation pathway, an important cell detoxification mechanism, showing significantly increased expression of genes associated with this pathway (15 genes out of 36 were affected

The loss of the maternal allele of chromosome 15q11-q13 causes Angelman syndrome [88], associated with epilepsy, intellectual disability, limited speech and truncal ataxia [58]