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This is exemplified by the context-dependent effect of statins, which may inadvertently exacerbate cholesterol starvation in CD8 + T cells, leading to profound suppression of their activation and survival [73, 113]

RSUME, a small RWD-containing protein, enhances SUMO conjugation and stabilizes HIF-1 during hypoxia

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Additionally, the attachment of a C-20 fatty diacid via -glutamyl spacer increases the duration of action by binding to albumin [82]

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