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In a few others, LDL was undetectable, or very low, reflecting phenotypes of severe hypobeta that led to problems of intestinal fat absorption and neurologic problems (8) (see also Chapter 8)

The genotypes were confirmed by PCR and Sanger sequencing (Cornell University Institute of Biotechnology)

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33 For young adults (age 2039), a 2018 expert panel recommended cholesterol-lowering therapy for those with LDL cholesterol over 160 mg/dL and a history of early-onset atherosclerosis in a close family member