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doi: 10.1083/jcb.123.2.293

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Since INS-1E cells are rat-derived, we used the mRNA sequence encoding rat 2A -adrenergic receptor as a template to generate guide RNA (gRNA) to disrupt the promoter region of the Adra2a gene (gRNA sequence: 5-GCAGCCGGATGCCGGCAATA-3, positions 5776)

When the bursa gets infected, it will produce fluid, get red and swell, resulting in pain

Link Completed and published clinical trial results can be sourced using databases such as Medline or Embase
