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Male Sprague-Dawley rats were used for behavioral testing, with 24-month-old rats of mixed sex also included for aged rat models

MOTS-c, by contrast, is not derived from hGH at all its research relevance comes from mitochondrial retrograde signaling, a communication pathway between mitochondria and the rest of the cell that governs how energy production adapts under metabolic stress

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Here is the honest order by evidence quality, not by hype: Cerebrolysin: most human studies, used in some countries for stroke and dementia Semax: decades of Russian research for stroke and cognition Selank: moderate human data, mainly anxiety Noopept: substantial research, mostly Russian, often sold as a nootropic Dihexa, P21, NSI-189: preclinical or very early, human data thin to absent Which peptide is best for memory