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In addition to systemic adverse effects, inhibiting BCL-2 family members could be problematic for diseases and conditions of the CNS

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The most practical ceiling for self-directed use is conservative: start near 1,000 mg/day, judge tolerance, and avoid assuming higher doses create better results

Investigated various glutathione derivatives in vitro and found that certain forms (e.g., GSHMEE) effectively reduce melanin and tyrosinase activity, increasing the pheomelanin/eumelanin ratio

Gastrointestinal dysfunction in Parkinson's disease
