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Hypothalamic and Hormonal Disruption MSG crosses the blood-brain barrier and affects the hypothalamus, the brain region that regulates: Hunger and satiety Reproductive hormones Stress and cortisol balance Rodent studies have shown that MSG exposure in early life causes obesity, infertility, and disrupted HPA axis signaling later in life

A., Miller, R

FEBS Lett 587:20082017

Newer evidence suggests that presence of mucus plugs increases all-cause mortality in COPD patients even in Global Initiative for Chronic Obstructive Lung Disease (GOLD) Stage 1 and proposes an early role for thiol based mucolytics for better disease outcomes (18, 19)

10.1126/science.abc4552 Science 111 ShafferC.GaddyJ.LohJ.JohnsonE.HillS.HennigE.et al (2011)