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Such phosphorylation leads to the blockade of the tyrosine residues in IRSs, to which the insulin and IGF-1 receptors phosphorylate to activate IRSs and consequently commence the signalling cascade [185, 192], as comprehensively discussed above
(c) Krebs Cycle, illustrating its connection to glycolysis, Electron Transport Chain, and Fatty Acid Beta-Oxidation pathway
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