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Description
These findings suggest that NNMT inhibition may influence tumor cell line phenotypes in vitro through both metabolic and epigenetic mechanisms, making 5-amino-1MQ a valuable tool for investigating the metabolic characteristics of different tumor cell lines

Human liver nicotinamide N-methyltransferase: cDNA cloning, expression, and biochemical characterization

Primary Mechanism: Selective NNMT Inhibition and NAD+ Restoration

Scientific Reports

5-Amino-1MQ has high membrane permeability, meaning it absorbs well and reaches target tissues effectively
