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The compound's selectivity extends to its membrane permeability characteristics, which allow efficient cellular uptake without affecting membrane integrity or cellular viability up to 100 M concentrations
Nature Chemical Biology 9(5):300-306
BioMed Research International 2021:9924314
The downstream effects of NNMT inhibition by 5-amino-1MQ create a cascade of beneficial metabolic changes at the cellular level
Mass spectrometry (LC-MS) identity confirmation
