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Modification of peptides to such a D-Retro Inverso (DRI)-isoform can render peptides new chemical properties, which may improve their potency in vitro and in vivo (Borsello et al., 2003)

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If any side effect persists or worsens, contact your prescriber promptly

Given our in vitro evidence that LCN2 promotes osteocyte ferroptosis, we next examined whether Lcn2 ablation in osteocytes alters expression of ferroptosis-related genes (FRGs) in vivo

Therefore, it is necessary to design a clinical trial based on the physiology of the system of interest in order to accurately assess the effect of vitamin D in the body