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Cognition & nootropic Most-searched use: investigated in research as a nootropic for memory, learning, and mental performance

Brain GABA and glutamate levels across pain conditions: A systematic literature review and meta-analysis of 1H-MRS studies using the MRS-Q quality assessment tool

A synergic antineoplastic effect was observed when CQ was used in combination with radiotherapy on U87 glioma initiating cells (U87 GICs) with respect to either radiation or CQ treatment alone, through apoptosis induction and autophagy inhibition, promoting cell cycle arrest in the G 0 /G 1 phase, increasing the expression of caspase-3, and decreasing the expression of Bcl-2 and autophagosome formation [267]

doi: 10.1007/s00109-017-1592-7 136 BorrmannHMcKeatingJAZhuangX

Abstract Background The insulin/IGF-1 signaling pathway has a major role in the regulation of longevity both in Caenorhabditis elegans and mammalian species, i.e., reduced activity of this pathway extends lifespan, whereas increased activity accelerates the aging process
