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However, the direct evidences to verify BA activated brain FXR signaling in regulating brain function still need to be further explored
The biological environment in which they work dramatically affects their effectiveness

Endogenous levels of MOTS-c appear to change with age, which provides clues to its role in the aging process

Some of the possible factors that are abundant in CS are polyaromatic hydrocarbons (PAHs) that are inducers of cytochrome P450s and are well known sources of reactive oxygen species [28]

The coordinated clearance of maternal factors including NLRP5, OOEP, and other SCMC components serves as a quality control checkpoint that must be successfully completed for normal development to proceed [98]
