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6 Windows of epigenetic plasticity to re-direct health trajectories to positive outcomes In summary, there appears to be a common denominator in the trajectories of stress-related disorders that we propose involves an epigenetic embedding of early life experiences through the mitochondrial metabolite LAC acting as part of a critical network system with other important mediators of brain plasticity and function, and that, when supplemented, rapidly alters gene expression profiles to ameliorate behaviors and cognitive function in animal models deficient in LAC because of stress-induced causes

van De Sande MMH, van Buul VJ, Brouns FJPH

doi: 10.3389/fendo.2022.810242, 223

In our study, sperm motility, deformity rates and the sperm counts of rats from the high-altitude model were assessed, and a preliminary analysis of sperm morphology was performed

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