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Notably, acetylcarnitine can act as an acetyl donor [37], supporting the acetylation process of cells through the shuttle mechanism of acetylcarnitine in the absence of conventional acetyl-CoA synthetase enzymes such as ATP-citrate lyase (ACLY) and acyl-CoA synthetase short chain 2 (ACSS2) [38]

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Recommended intake: Cons ume 1 g daily with sufficient liquid

Messano, A

As the search for blood-based biomarkers in ME/CFS and Long COVID continues to evolve, metabolic panels measuring acylcarnitine and other mitochondrial intermediates are becoming increasingly recognized as vital diagnostic tools