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CONCLUSION This review aimed to elucidate the principal mechanisms involved in the neuropsychiatric manifestations of COVID-19, which involve glutamate dysregulation, Xct, Nf-B, mGluR2, and mGluR3, astrocyte and glial damage and neurotoxicity highlighted as central factors [15], exploring the potential of NAC and ALC as promising therapeutic agents in neuropsychiatric conditions COVID-19-related, including those associated with PCS

Mice that received choline intraperitoneally before and during sepsis exhibit lower levels of plasma blood urea nitrogen (BUN) and creatinine, as well as urine neutrophil gelatinase-associated lipocalin (NGAL) levels compared to septic mice treated with vehicle

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Iglehart I, Lederman S, Kelley M, Vaughn B, Engels J, Sullivan G.POS0324 TARGETING NON-RESTORATIVE SLEEP IN FIBROMYALGIA WITH BEDTIME TNX-102SL (SUBLINGUAL CYCLOBENZAPRINE HCL) SIGNIFICANTLY IMPROVES PAIN INRESILIENT, A CONFIRMATORY PHASE 3 RANDOMIZED CLINICAL TRIAL
