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Funding This work was supported by Priority Union Foundation of Yunnan Provincial Science and Technology Department and Kunming Medical University (No.202201 AY070001 - 066), Funding of the"famous doctors"project of the support plan for the talents of Xingdian (No.RLMY20220005), The scientific and technological innovation team of Kunming Medical University (CXTD202209), Yunnan Provincial Endocrinology and Metabolism Clinical Medicine Center (YWLCYXZXXYS20221005),Clinical Collaboration Project of Traditional Chinese and Western Medicine for Major Difficult Diseases of Yunnan Province (300073)

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10.1016/j.cell.2022.04.020 147 PatelH.McintireJ.RyanS.DunahA.LoringR

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