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Cabassi, F

Coumarin-dithiocarbamate hybrids as novel multitarget AChE and MAO-B inhibitors against Alzheimers disease: Design, synthesis and biological evaluation

A pharmaceutical-grade compounding setup with proper buffering and cold-chain storage produces stable formulations

Data shows a short half-life and bioavailability of about 30% of ALA due to mechanisms involving hepatic degradation, reduced ALA solubility as well as instability in the stomach
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