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The laboratory animals with the Specific Pathogen-Free (SPF) status were procured from the Research Institute of Pharmacology of Living Systems at the Belgorod State University (Belgorod, Russian Federation)

Methionine is an essential amino acid and a precursor for S-adenosylmethionine (SAM), a vital methyl donor in various biochemical reactions (, , , , )

Notably, melanin is critical for the stress response of C

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The quantification of organic acids composition in kombucha tea at different fermentation stages (0, 3, 6, 9, 12, and 15 days) was conducted using high-performance liquid chromatography (HPLC), with results presented in supplementary data (supplementary Table S1)