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It is urgent to develop new specific agents against HSV-1 infection due to the universality of HSV-1 infection and the limitations of existing clinical drugs (Sadowski et al., 2019

[DOI] [PubMed] [Google Scholar] Hiranita T, Obeng S, Sharma A, Wilkerson JL, McCurdy CR, McMahon LR (2022) In vitro and in vivo pharmacology of kratom

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Natural bioactive compounds derived from plants have also demonstrated benefits in preclinical and clinical studies for ASD management [132]

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