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E.BallaranoC

To determine whether irisin ameliorates neuronal damage via the SIRT1 pathway, we assessed SIRT1 expression

10.1016/j.archger.2023.105255 296 ZhaoY.LuZ.ZhangH.WangL.SunF.LiQ.et al (2025)

In general, low levels of ROS production can result in cell proliferation and activation of antioxidant defenses, but higher ROS levels trigger DNA damage, p53 activation, cell cycle blockade, and cell death via apoptosis and/or necrosis

Dupont J, Scaramuzzi RJ
