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A meta-analysis of 18 RCTs confirmed PRPs superiority over placebo and corticosteroid injections, highlighting long-term benefits in pain reduction and tendon healing (PMID: 32073993)
Rather than directly activating GABA-A receptors, the peptide appears to maintain homeostasis of the entire GABA receptor complex, preventing the desensitization and compensatory changes that produce tolerance and dependence
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Endocrinology 134 , 24042409 (1994)
