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Rowe JD, Nieves E, Listowsky I
We hypothesized that disrupting this tether or lengthening the linker that connects the two -CTs may uncouple the two binding sites in the active state of IGF1R, reduce the negative cooperativity, and allow the binding of the second IGF1
Compared to the control group under hypoxic culture, GBM cell growth rate was found to be increased with inhibited cell invasion (164)
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