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when the intracellular Fe2+ overload exceeds the caching capacity of ferritin, and intracellular free iron generates ROS through the fenton reaction, and glutathione (GSH), one of the critically important antioxidants in cells, is catalyzed by peroxidase to oxidized glutathione (GSSG) during lipid peroxidation, and inhibit lipid peroxidation-induced ferroptosis (119)

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K13497 encodes an enzyme involved in tryptophan synthesis, which produces pyruvate (a precursor of SCFAs), among other products (Fig
