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Description
Parkinsons disease, and proof-of-concept clinical trials
Mac Nelly A, Kai M, Svato A, Diekert G, Schubert T (2014) Functional heterologous production of reductive dehalogenases from Desulfitobacterium hafniense strains
The nervous system withstands ageing better than other organs and systems (a phenomenon recognised long ago 516 ), which arguably reflects the high plastic potential allowing constant remodelling of the nervous tissue (the process which underlines life-long learning and adaptation) and high defensive and regenerative potential of neuroglia defining nervous system resilience and regeneration mending various insults accumulating during life-span
Intravenous administration might be better in some cases
In turn, the mRNA reduced neurotoxicity and neuroinflammation in both in vitro and in vivo PD models
