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Silymarin also affects -amyloid aggregation, inflammatory mechanisms, cellular apoptotic machinery, and estrogenic receptor mediation

doi: 10.1016/S1567-5769(01)00088-1 67 KolbertZ.FeiglG.FreschiL.PorP

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Meanwhile, GQD also inhibited the expression of pro-inflammatory cytokines, such as TNF-, IL-1, and IL-6, and attenuated inflammation and tissue damage in the colon (Liu et al., 2021)

Glucocorticoids remain the first-line therapy, but their use carries a dose-dependent risk of severe adverse events (40)