glutathione peroxidase antioxidant 2 - an overview Enzymatic and Non enzymatic defense

Mechanistically, ox-LDL induces lipid peroxidation by inhibiting the SREBP-1/SCD1/FADS2-mediated lipid biosynthesis pathway, leading to endothelial damage and ultimately inducing ferroptosis ( 3.3 Ferroptosis and the inflammatory response The discovery of ferroptosis may explain iron accumulation's biological effects

2005:549-563 Gorouhi, F

[33] However, it is not always feasible, nor does it necessarily overcome offtarget phototoxicity within tumouradjacent normal tissue that remain inside light irradiation zones

These are commonly referred to as ROS

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