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The SCARJ1 protein is encoded by the AGER (advanced glycosylation end-product specific receptor) gene

Pre-incubation (24 h) of differentiated human THP-1 macrophages with STW3-VI (80 or 100 g/ml) significantly ( p 0.01) reduced the LPS-EB (0.01 g/ml)-induced TNF release by 47.3 and 53.8% (Figure 5B)

Elastic fibers (mainly elastin and associated microfibrils (e.g., fibrillin)) are essential for both the structural integrity of alveolar septa and small airways and tethering of alveoli and bronchioles, ensuring, thus, mechanical recoil during exhalation and preventing alveoli and bronchiole overdistention and collapse, respectively

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