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ABSTRACT Coffee enemas are believed to cause dilatation of bile ducts and excretion of bile through the colon wall

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this deficit may be pathoplastic and influence the treatment outcomes [e.g., treatment resistance ( In addition to the above considerations, it is also likely that the use of antipsychotics and other medications as well as a high degree of variability in lifestyle factors and daily functioning (including diet) may make the patient group more heterogenous