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390 Generally smaller sized NPs have enhanced antibacterial activity as a result of increased surface area that comes into proximity with the microbial cell

However, evidence of safety and efficacy in humans, depending on the peptide, ranges from thin to nonexistent

As illustrated in Figure 2, pyroptosis is a form of programmed cell death mediated by inflammasomes, in which activation of the NLRP3 inflammasome triggers caspase-1

At least 3 biological replicates were analyzed per line

Conclusions Current evidence supports the use of NAC in patients with ALF of different etiologies as it may be associated with potential benefits in survival and remission of liver injury due to its effects on both pro-inflammatory cytokines and reactive oxygen species