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Finally, a microplate spectrophotometer (Envision, PerkinElmer, Waltham, MA) was used to detect the OD values at 450 nm

Jan 2014;141(1):1-12

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[DOI] [PMC free article] [PubMed] [Google Scholar] 36.Minshawi N.F., Wink L.K., Shaffer R., Plawecki M.H., Posey D.J., Liu H., Hurwitz S., McDougle C.J., Swiezy N.B., Erickson C.A

On the other hand, PDE5 degrades cGMP, which disrupts the vasodilatory pathway initiated by NO
