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Elias (1983) introduced the concept of the stratum corneum as a wall composed of corneocyte bricks sealed together with a lipid mortar composed of a mixture of ceramide, cholesterol, and fatty acids, which was replicated as a topical barrier-repair therapy for eczema (Elias, 2022
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Yet from the FDAs perspective, much of the evidence remained fragmented
Specifically, we examined portal and inferior caval vein hypertension
